Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.53 |
| ▸ | ACE | P12821 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027559 | 1.00 | MME (0.53) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL8026918 | 0.87 | MME (0.43) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL27464506 | 0.87 | MME (0.43) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL8026913 | 0.87 | MME (0.43) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL8033722 | 0.83 | MME (0.56) | MMEACESMN1; SMN2CA12CA1 | |
| SCHEMBL8033718 | 0.83 | MME (0.56) | MMEACESMN1; SMN2CA12CA1 | |
| SCHEMBL10660237 | 0.80 | MME (0.37) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL8028702 | 0.78 | MME (0.61) | MMEACESMN1; SMN2CA2 | |
| SCHEMBL8453835 | 0.78 | MME (0.61) | MMEACESMN1; SMN2CA2 | |
| SCHEMBL8028700 | 0.78 | MME (0.61) | MMEACESMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |