Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.37 |
| ▸ | ACE | P12821 | 6/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 5/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662290 | 0.80 | MME (0.54) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8027559 | 0.80 | MME (0.53) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL8027558 | 0.80 | MME (0.53) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL10665614 | 0.76 | PSEN1 (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30477098 | 0.76 | CTSD (0.41) | MMESLC7A5ALDH1A1 | |
| SCHEMBL27464506 | 0.74 | MME (0.43) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL8026913 | 0.74 | MME (0.43) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL8026918 | 0.74 | MME (0.43) | MMEACESMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL10656917 | 0.73 | ENPEP (0.44) | ALDH1A1 | |
| SCHEMBL10656924 | 0.73 | ENPEP (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757050-A | Urea, amide group-containing | E. R. SQUIBB SONS, INC. (US) | 1988-07-12 | — | — | US | disclosed |