Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8610669 | 0.86 | OPRM1 (0.49) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| SCHEMBL8026775 | 0.86 | OPRK1 (0.59) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| SCHEMBL8026878 | 0.86 | SLC6A2 (0.71) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| Hydrochloric Acid SCHEMBL8612507 | 0.85 | SLC6A2 (0.70) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| Hydrochloric Acid SCHEMBL8610658 | 0.85 | OPRK1 (0.58) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| SCHEMBL8025053 | 0.84 | SLC6A2 (0.57) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| SCHEMBL8024618 | 0.83 | OPRK1 (0.61) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| Hydrochloric Acid SCHEMBL8616069 | 0.83 | SLC6A2 (0.56) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| Hydrochloric Acid SCHEMBL8614236 | 0.83 | OPRK1 (0.60) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 | |
| O-Desmethyl Tramadol SCHEMBL4396389 | 0.82 | OPRM1 (1.00) | OPRM1SLC6A4OPRK1SLC6A2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| EP-0780369-A1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-06-25 | — | — | EP | disclosed |