Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 19/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.59 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.59 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.59 |
| ▸ | PRKCG | P05129 | 3/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.59 |
| ▸ | PHKG2 | P15735 | 3/20 | 0.59 |
| ▸ | MARK3 | P27448 | 3/20 | 0.59 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.59 |
| ▸ | CLK2 | P49760 | 3/20 | 0.59 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.59 |
| ▸ | NEK4 | P51957 | 3/20 | 0.59 |
| ▸ | CSNK1G2 | P78368 | 3/20 | 0.59 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.59 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.59 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.59 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028173 | 0.98 | ITK (0.59) | ITKCSNK1DRPS6KA3DYRK1AAURKB | |
| SCHEMBL8028272 | 0.87 | CNR2 (0.60) | ITKCSNK1DRPS6KA3DYRK1AAURKB | |
| Hydrochloric Acid SCHEMBL8031513 | 0.87 | ITK (0.51) | ITKCSNK1DRPS6KA3DYRK1AAURKB | |
| Hydrochloric Acid SCHEMBL8028490 | 0.85 | ITK (0.50) | ITKCSNK1DRPS6KA3DYRK1AAURKB | |
| SCHEMBL8030096 | 0.82 | NPC1 (0.47) | ITKCSNK1DRPS6KA3DYRK1AAURKB | |
| SCHEMBL8026960 | 0.80 | CNR2 (0.51) | ITKCNR2 | |
| SCHEMBL8026447 | 0.77 | F2 (0.41) | CNR2 | |
| SCHEMBL8026373 | 0.77 | CNR2 (0.46) | CNR2 | |
| SCHEMBL8028165 | 0.77 | CNR2 (0.43) | ITKCNR2 | |
| SCHEMBL8031603 | 0.77 | CNR2 (0.47) | ITKCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |