Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.50 |
| ▸ | LOX | P28300 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27511614 | 0.91 | MAPT (0.53) | HTR6LOXALDH1A1PKMMAPT | |
| SCHEMBL30166976 | 0.80 | HTR6 (0.74) | HTR6LOXALDH1A1PKMMAPT | |
| SCHEMBL950448 | 0.80 | HTR6 (0.74) | HTR6LOXALDH1A1PKMMAPT | |
| SCHEMBL8026758 | 0.78 | KMT2A (0.51) | HTR6LOXALDH1A1PKMMAPT | |
| SCHEMBL1503399 | 0.77 | GAA (0.55) | HTR6ALDH1A1PKMMAPTPOLB | |
| SCHEMBL28784731 | 0.76 | HTR6 (0.52) | HTR6LOXALDH1A1PKMMAPT | |
| SCHEMBL13147946 | 0.76 | HTR6 (0.50) | HTR6LOXALDH1A1MAPTPOLB | |
| SCHEMBL11645123 | 0.75 | PRMT1 (0.58) | CYP2C9 | |
| SCHEMBL4615892 | 0.75 | HTR6 (0.52) | HTR6ALDH1A1PKMMAPTPOLB | |
| SCHEMBL1368816 | 0.75 | ALDH1A1 (0.64) | HTR6ALDH1A1PKMMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |