Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680971 | 0.90 | EP300 (0.60) | ALDH1A1HTTSMN1; SMN2LMNAEP300 | |
| SCHEMBL8030148 | 0.84 | ALDH1A1 (0.56) | ALDH1A1GAATRPV1EP300POLB | |
| SCHEMBL7933998 | 0.83 | ALDH1A1 (0.55) | ALDH1A1GAATRPV1EP300POLB | |
| SCHEMBL8016606 | 0.83 | ALDH1A1 (0.55) | ALDH1A1GAATRPV1EP300POLB | |
| SCHEMBL4604147 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HTTSMN1; SMN2LMNAGAA | |
| SCHEMBL29728210 | 0.81 | MAPT (0.68) | ALDH1A1HTTSMN1; SMN2LMNAGAA | |
| SCHEMBL4867099 | 0.81 | MAPT (0.68) | ALDH1A1HTTSMN1; SMN2LMNAGAA | |
| SCHEMBL8032577 | 0.79 | TSHR (0.58) | ALDH1A1HTTGAATRPV1EP300 | |
| SCHEMBL27404464 | 0.79 | ALDH1A1 (0.51) | ALDH1A1GAATRPV1EP300POLB | |
| SCHEMBL10957416 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HTTSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603954-B1 | Immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer | JOHNSON & JOHNSON CLIN DIAG (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0603953-B1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | JOHNSON & JOHNSON CLIN DIAG (US) | 1999-02-17 | — | — | EP | disclosed |
| US-5736335-A | Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents | EASTMAN KODAK COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5641635-A | Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents | EASTMAN KODAK COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| US-5372932-A | Peroxidase-labeled immunoreactant; stabiliztion with a 4-hydroxy or 4-alkoxyarylacetamide | EASTMAN KODAK COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| EP-0603953-A1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0603954-A2 | Analytical element and immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |