Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207226 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TP53RNPEPL3MBTL1 | |
| SCHEMBL8028253 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TP53RNPEPL3MBTL1 | |
| SCHEMBL10521929 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TP53RNPEPL3MBTL1 | |
| SCHEMBL8028244 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TP53RNPEPL3MBTL1 | |
| SCHEMBL10521900 | 0.84 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL10521255 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TP53L3MBTL1 | |
| SCHEMBL6207891 | 0.80 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1 | |
| SCHEMBL2232837 | 0.80 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1 | |
| SCHEMBL8028251 | 0.80 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1 | |
| SCHEMBL17909976 | 0.78 | ALDH1A1 (0.35) | ALDH1A1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979244-A1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998049193-A1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1998-11-05 | — | — | WO | disclosed |