Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935776 | 0.79 | OPRD1 (0.66) | OPRD1OPRM1OPRK1 | |
| SCHEMBL2752684 | 0.79 | OPRD1 (0.66) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8028515 | 0.76 | OPRD1 (0.57) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6654151 | 0.75 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6654141 | 0.75 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6654146 | 0.75 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7971485 | 0.75 | OPRD1 (0.52) | OPRD1OPRM1OPRK1 | |
| SCHEMBL15764534 | 0.74 | OPRD1 (0.81) | OPRD1OPRM1OPRK1 | |
| SCHEMBL252534 | 0.74 | OPRD1 (0.81) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6652027 | 0.73 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983251-A1 | ANTI-INFLAMMATORY PIPERAZINYL-BENZYL-TETRAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | Pfizer Limited (GB) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052929-A1 | ANTI-INFLAMMATORY PIPERAZINYL-BENZYL-TETRAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | PFIZER LIMITED (GB) | 1998-11-26 | — | — | WO | disclosed |