Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651777 | 0.77 | OPRD1 (0.54) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL6651784 | 0.77 | OPRD1 (0.54) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL6651771 | 0.77 | OPRD1 (0.54) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL6652888 | 0.76 | OPRD1 (0.54) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL6655500 | 0.76 | P2RX7 (0.57) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL6655511 | 0.76 | P2RX7 (0.57) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL6655504 | 0.76 | P2RX7 (0.57) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL6652878 | 0.76 | OPRD1 (0.54) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL6652876 | 0.76 | OPRD1 (0.54) | OPRD1ATMHDAC1MEN1KMT2A | |
| SCHEMBL2751728 | 0.76 | OPRD1 (0.72) | OPRD1ATMHDAC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983251-A1 | ANTI-INFLAMMATORY PIPERAZINYL-BENZYL-TETRAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | Pfizer Limited (GB) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052929-A1 | ANTI-INFLAMMATORY PIPERAZINYL-BENZYL-TETRAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | PFIZER LIMITED (GB) | 1998-11-26 | — | — | WO | disclosed |