SCHEMBL8028496

SCHEMBL8028496

CC1CC=C(C(=O)Br)CC1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
CES2 O00748 1/20 0.40
TSHR P16473 1/20 0.40
ALDH1A1 P00352 1/20 0.33
CYP2C19 P33261 1/20 0.33
GABRR1 P24046 2/20 0.31
CCR2 P41597 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1780881 0.82 LMNA (0.44) LMNACES2TSHRALDH1A1CYP2C19
SCHEMBL13745963 0.82 CES2 (0.58) LMNACES2TSHRALDH1A1CYP2C19
SCHEMBL2874581 0.82 CES2 (0.58) LMNACES2TSHRALDH1A1CYP2C19
SCHEMBL10066924 0.82 LMNA (0.44) LMNACES2TSHRALDH1A1CYP2C19
SCHEMBL18614512 0.82 LMNA (0.44) LMNACES2TSHRALDH1A1CYP2C19
SCHEMBL2879186 0.80 CES2 (0.40) LMNACES2TSHRALDH1A1CYP2C19
SCHEMBL13457693 0.80 GABRR1 (0.47) LMNACES2TSHRALDH1A1CYP2C19
Hydrochloric Acid SCHEMBL2879189 0.80 CES2 (0.56) LMNACES2TSHRALDH1A1CYP2C19
Bromide SCHEMBL9860546 0.80 CES2 (0.56) LMNACES2TSHRALDH1A1CYP2C19
SCHEMBL14231199 0.80 GABRR1 (0.47) LMNACES2TSHRALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6048933-A HYDROGENATED BLOCK POLYMERS AND PEROXIDE CROSSLINKING AGENTS RIKEN VINYL INDUSTRY CO., LTD. (JP) 2000-04-11 US disclosed
EP-0770645-B1 Thermoplastic elastomeric resin composition and a process for the preparation thereof RIKEN VINYL IND (JP) 2000-02-02 EP disclosed
US-5929165-A HEAT TREATING POLYMERIC BLOCKS COMPOSED MAINLY OF A VINYL AROMATIC COMPOUND AND AT LEAST ONE POLYMERIC BLOCK COMPOSED MAINLY OF A CONJUGATED DIENE COMPOUND WITH A PEROXY CROSSLINKER RIKEN VINYL INDUSTRY CO., LTD. (JP) 1999-07-27 US disclosed
EP-0735056-B1 Catalyst for the polymerization of olefines and processes for the polymerization of olefines using the same TONEN CORP (JP) 1998-06-10 EP disclosed
US-5747595-A TRIALKOXYALKYLSILANE TONEN CORPORATION (JP) 1998-05-05 US disclosed
EP-0770645-A2 Thermoplastic elastomeric resin composition and a process for the preparation thereof RIKEN VINYL INDUSTRY CO., LTD. (JP) 1997-05-02 EP disclosed
EP-0735056-A1 Catalyst for the polymerization of olefines and processes for the polymerization of olefines using the same Tonen Corporation (JP) 1996-10-02 EP disclosed
EP-0425701-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TONEN CORP (JP) 1995-09-13 EP disclosed
EP-0425702-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TONEN CORP (JP) 1995-09-13 EP disclosed
US-5177043-A α-olefin polymerization catalyst component TONEN CHEMICAL CORPORATION (JP) 1993-01-05 US disclosed
EP-0173472-A2 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-03-05 EP disclosed
EP-0173470-A2 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-03-05 EP disclosed
EP-0171155-A1 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-02-12 EP disclosed
EP-0171200-A2 Catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-02-12 EP disclosed
US-4565798-A COORDINATION CATALYSTS, TITANIUM, MAGNESIUM, SILICON COMPOUND TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-01-21 US disclosed
EP-0157472-A1 Process for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-10-09 EP disclosed
EP-0156512-A1 Process for preparing catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-10-02 EP disclosed
EP-0147053-A1 A catalyst and a process for polymerization of olefins Tonen Corporation (JP) 1985-07-03 EP disclosed
EP-0145368-A2 Process for producing propylene block copolymers TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-06-19 EP disclosed
EP-0044635-A1 Catalyst components for polymerization of alpha-olefins and a method for using them TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1982-01-27 EP disclosed