Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2620087 | 1.00 | HCRTR1 (0.38) | HCRTR1HCRTR2AAK1PSMB8 | |
| SCHEMBL932766 | 0.86 | HCRTR1 (0.37) | HCRTR1HCRTR2AAK1 | |
| SCHEMBL6874988 | 0.86 | HCRTR1 (0.37) | HCRTR1HCRTR2AAK1 | |
| SCHEMBL2926279 | 0.86 | ALDH1A1 (0.35) | — | |
| SCHEMBL2926274 | 0.86 | ALDH1A1 (0.35) | — | |
| SCHEMBL8028507 | 0.83 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL2620086 | 0.83 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL933488 | 0.77 | HCRTR1 (0.37) | HCRTR1HCRTR2AAK1 | |
| SCHEMBL2119277 | 0.76 | — | — | |
| SCHEMBL2107447 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |