SCHEMBL8028656

SCHEMBL8028656

CCCCCCCCCCC(C(=O)OCCCCCC)S(=O)(=O)O

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.47
RECQL P46063 1/20 0.47
EPHX1 P07099 1/20 0.44
TSHR P16473 3/20 0.43
ZDHHC7 Q9NXF8 1/20 0.42
MAPT P10636 1/20 0.42
TP53 P04637 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41
RAD52 P43351 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
FAAH O00519 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
ACHE P22303 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4927432 0.98 NAAA (0.46) NAAARECQLEPHX1TSHRZDHHC7
SCHEMBL1483766 0.95 RECQL (0.46) NAAARECQLEPHX1TSHRZDHHC7
SCHEMBL16642004 0.93 RECQL (0.47) NAAARECQLEPHX1ZDHHC7MAPT
SCHEMBL10337863 0.91 FAAH (0.48) RECQLMAPTNPSR1FAAHLMNA
SCHEMBL8831593 0.90 RECQL (0.44) RECQLTSHRZDHHC7MAPTTP53
SCHEMBL27428335 0.90 RECQL (0.44) RECQLTSHRZDHHC7MAPTTP53
SCHEMBL8831176 0.90 RECQL (0.44) RECQLTSHRZDHHC7MAPTTP53
SCHEMBL8569266 0.89 RECQL (0.42) NAAARECQLEPHX1TSHRZDHHC7
SCHEMBL27395385 0.88 RECQL (0.48) RECQLTSHRZDHHC7MAPTTP53
SCHEMBL9621468 0.88 RECQL (0.48) RECQLTSHRZDHHC7MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0631611-B1 NEUTRAL pH CLEANSING BAR PROCTER & GAMBLE (US) 2000-02-02 EP disclosed
EP-0631614-B1 SKIN pH CLEANSING BAR PROCTER & GAMBLE (US) 1999-06-09 EP disclosed
EP-0559837-B1 SHAPED SOLID MADE WITH A RIGID, INTERLOCKING MESH OF NEUTRALIZED CARBOXYLIC ACID PROCTER & GAMBLE (US) 1995-10-25 EP disclosed
EP-0631611-A1 NEUTRAL pH CLEANSING BAR THE PROCTER & GAMBLE COMPANY (US) 1995-01-04 EP disclosed
EP-0631614-A1 SKIN pH CLEANSING BAR THE PROCTER & GAMBLE COMPANY (US) 1995-01-04 EP disclosed
EP-0594703-A1 A PERSONAL CLEANSING FREEZER BAR MADE WITH A RIGID, INTERLOCKING MESH OF NEUTRALIZED CARBOXYLIC ACID. PROCTER & GAMBLE (US) 1994-05-04 EP disclosed
US-5264145-A Personal cleansing freezer bar with selected fatty acid soaps and synthetic surfactant for reduced bathtub ring, improved mildness, and good lather THE PROCTER & GAMBLE COMPANY (US) 1993-11-23 US disclosed
WO-1993019154-A1 NEUTRAL pH CLEANSING BAR THE PROCTER & GAMBLE COMPANY (US) 1993-09-30 WO disclosed
WO-1993019159-A1 SKIN PH CLEANSING BAR THE PROCTER & GAMBLE COMPANY (US) 1993-09-30 WO disclosed
WO-1993002174-A1 A PERSONAL CLEANSING FREEZER BAR MADE WITH A RIGID, INTERLOCKING MESH OF NEUTRALIZED CARBOXYLIC ACID THE PROCTER & GAMBLE COMPANY (US) 1993-02-04 WO disclosed