Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 7/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8032368 | 0.85 | F2 (0.58) | F2USP2ALDH1A1HSD17B10ALOX15 | |
| SCHEMBL8028430 | 0.82 | CNR2 (0.57) | F2ITKAURKAMAP4K4CHEK2 | |
| SCHEMBL8026604 | 0.78 | F2 (0.47) | F2ALDH1A1HSD17B10ITKAURKA | |
| SCHEMBL8031763 | 0.76 | PKM (0.52) | USP2ALDH1A1HSD17B10ALOX15MAPK1 | |
| SCHEMBL8026572 | 0.76 | ITK (0.57) | F2ITKAURKAMAP4K4CHEK2 | |
| SCHEMBL8028940 | 0.75 | ITK (0.60) | F2ITKAURKAMAP4K4CHEK2 | |
| SCHEMBL8016797 | 0.73 | F2 (0.71) | F2CNR2ACSL1POLBMEN1 | |
| SCHEMBL8139393 | 0.73 | CNR2 (0.59) | USP2ITKCNR2CNR1POLB | |
| SCHEMBL7115133 | 0.71 | ITK (0.47) | F2ITKAURKAMAP4K4CHEK2 | |
| SCHEMBL8032935 | 0.70 | F2 (0.49) | F2USP2ITKACSL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |