Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | JUN | P05412 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031841 | 0.90 | KDM4E (0.60) | ALOX5KDM4EMAPTRECQLHTT | |
| SCHEMBL30075809 | 0.83 | TP53 (0.60) | ALOX5KDM4EMAPTRECQLHTT | |
| SCHEMBL8028622 | 0.82 | ALOX5 (0.56) | ALOX5KDM4EMAPTRECQLHTT | |
| SCHEMBL8034404 | 0.81 | ALOX5 (0.79) | ALOX5KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL8019019 | 0.80 | ALOX5 (0.54) | ALOX5KDM4EMAPTRECQLHTT | |
| SCHEMBL8030403 | 0.80 | ALOX5 (0.54) | ALOX5KDM4EMAPTRECQLHTT | |
| SCHEMBL8019021 | 0.80 | ALOX5 (0.54) | ALOX5KDM4EMAPTRECQLHTT | |
| SCHEMBL8019035 | 0.79 | TDP1 (0.71) | ALOX5KDM4EMAPTRECQLSMN1; SMN2 | |
| SCHEMBL25804735 | 0.79 | TDP1 (0.71) | ALOX5KDM4EMAPTRECQLSMN1; SMN2 | |
| SCHEMBL8028624 | 0.77 | KDM4E (0.60) | ALOX5KDM4EMAPTRECQLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063152-A1 | ACETYLATED AND RELATED ANALOGUES OF CHICORIC ACID AS HIV INTEGRASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-10-26 | — | — | WO | disclosed |