Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | CTSG | P08311 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030824 | 0.99 | HDAC6 (0.66) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8028984 | 0.89 | HDAC6 (0.68) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8019515 | 0.89 | HDAC6 (0.68) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8029208 | 0.88 | HDAC1 (0.66) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8019496 | 0.88 | HDAC6 (0.66) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8029037 | 0.87 | GAA (0.62) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL12672001 | 0.85 | NAAA (0.67) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8770687 | 0.84 | HDAC6 (0.73) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8032587 | 0.82 | HDAC1 (0.58) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL27419582 | 0.82 | GPR139 (0.55) | SMN1; SMN2PRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |
| CN-1046535-C | Erythromycin A 9-0-oxime derivatives endowed with antibiotic activity | ZAMBON SPA (IT) | 1999-11-17 | — | — | CN | disclosed |
| US-5847092-A | Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity | ZAMBON GROUP S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| CN-1169727-A | Erythromycin A 9-0-oxime derivatives endowed with antibiotic activity | ZAMBON SPA (IT) | 1998-01-07 | — | — | CN | disclosed |