SCHEMBL8029034

SCHEMBL8029034

CCCCC(C(=O)O)c1ccc(N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
PDE4D Q08499 1/20 0.42
POLB P06746 3/20 0.42
CPN1 P15169 2/20 0.41
CPB2 Q96IY4 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP13 P45452 1/20 0.40
GRM8 O00222 1/20 0.40
GRM7 Q14831 1/20 0.40
GRM4 Q14833 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6143732 0.95 LMNA (0.49) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL4423279 0.93 LMNA (0.51) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL22712583 0.89 LMNA (0.42) LMNACYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL6943616 0.84 LMNA (0.46) LMNACYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL10896682 0.84 POLB (0.49) LMNAPOLBALDH1A1CA2MAPK1
SCHEMBL455432 0.84 POLB (0.53) LMNACYP2C19POLBALDH1A1MAPT
SCHEMBL2489621 0.83 HTR7 (0.46) LMNAPOLBALDH1A1
SCHEMBL27751810 0.83 POLB (0.53) LMNACYP2C9CYP2C19POLBMMP9
SCHEMBL27541113 0.82 POLB (0.51) LMNACYP2C19POLBALDH1A1MAPT
SCHEMBL1767974 0.82 LMNA (0.47) LMNACYP1A2CYP3A4CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103495340-B The method of SOx in compound alcamines solution removal gas BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO.,LTD. (CN) 2015-11-18 CN claimed
CN-103495340-A Method of removing SOx in gas by compound alkanolamine solution BEIJING BOYUAN HENGSHENG HIGH TECHNOLOGY CO LTD 2014-01-08 CN claimed
EP-0701997-B1 Reaction products of anilines and bisphenolgylcidylethers, a process for their preparation and their use as hardening accelerators BAYER AG (DE) 2000-02-16 EP disclosed
EP-0701997-A1 Reaction products of anilines and bisphenolgylcidylethers, a process for their preparation and their use as hardening accelerators BAYER AG (DE) 1996-03-20 EP disclosed
US-4439448-A IMMUNOMODULATING ACTIVITY MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-03-27 US disclosed
EP-0052296-A1 Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives MITSUBISHI KASEI CORPORATION (JP) 1982-05-26 EP disclosed