Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923670 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1PKMMAPK1 | |
| SCHEMBL14909378 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1PKMMAPK1 | |
| SCHEMBL14909379 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1PKMMAPK1 | |
| SCHEMBL14928384 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1PKMMAPK1 | |
| SCHEMBL14928331 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1PKMMAPK1 | |
| SCHEMBL17559361 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1PKMMAPK1 | |
| SCHEMBL9773949 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPK1RAB9AMAPT | |
| SCHEMBL20777643 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1PKMMAPK1 | |
| SCHEMBL5328150 | 0.74 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPK1RAB9AKDM4E | |
| SCHEMBL8939993 | 0.74 | ALDH1A1 (0.64) | ALDH1A1KMT2AMAPK1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318777-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2012-11-27 | — | — | US | disclosed |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2012-03-22 | — | — | US | disclosed |
| US-8071627-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2011-12-06 | — | — | US | disclosed |
| US-7723363-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER CROPSCIENCE SA (FR) | 2010-05-25 | — | — | US | disclosed |
| US-7560567-B2 | 2-pyridinylethylbenzamide derivatives | BAYER CROPSCIENCE S.A. (FR) | 2009-07-14 | — | — | US | disclosed |
| US-20090088456-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as Fugicides | BAYER CROPSCIENCE S.A. | 2009-04-02 | — | — | US | disclosed |
| US-20070167491-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-07-19 | — | — | US | disclosed |
| US-20070117845-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER CROPSCIENCE S.A. (FR) | 2007-05-24 | — | — | US | disclosed |
| US-20070099965-A1 | 2-Pyridinylethylbenzamide derivatives | BAYER SAS (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088456-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as Fugicides | PFAS, CYP4F2, FPGS | ALDH1A1 1119/4885KMT2A 1855/4885MEN1 3558/4885 |
| US-20070117845-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | CYP1A2, PNPO, PFAS | ALDH1A1 1103/4885KMT2A 937/4885MEN1 1795/4885 |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP3A5 | ALDH1A1 831/4885KMT2A 817/4885MEN1 2328/4885 |
| US-20070099965-A1 | 2-Pyridinylethylbenzamide derivatives | CYP1A2, CYP4B1, CYP4F2 | ALDH1A1 772/4885KMT2A 1093/4885MEN1 1814/4885 |
| US-20070167491-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | CYP1A2, PNPO, PFAS | ALDH1A1 1103/4885KMT2A 937/4885MEN1 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.