Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28901571 | 0.83 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1KDM4EGAACES2 | |
| SCHEMBL6046964 | 0.76 | CES2 (0.39) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL28459741 | 0.72 | SRC (0.45) | L3MBTL1ALDH1A1KDM4EGAACXCR2 | |
| SCHEMBL5610465 | 0.71 | CES2 (0.61) | L3MBTL1ALDH1A1KDM4ECES2CES1 | |
| SCHEMBL11613250 | 0.70 | TSHR (0.44) | L3MBTL1ALDH1A1KDM4EGAATSHR | |
| SCHEMBL11414735 | 0.70 | TSHR (0.44) | L3MBTL1ALDH1A1KDM4EGAATSHR | |
| SCHEMBL6047008 | 0.70 | CES2 (0.33) | CES2CES1LMNASMN1; SMN2MAPT | |
| SCHEMBL7050570 | 0.69 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1KDM4EGAACXCR2 | |
| SCHEMBL31561697 | 0.69 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1KDM4EGAACXCR2 | |
| SCHEMBL20853408 | 0.69 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1KDM4EGAACXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |