Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685438 | 0.87 | CRBN (0.41) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL29125162 | 0.85 | CYP4F2 (0.43) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL4190795 | 0.79 | CRBN (0.46) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL10963440 | 0.79 | CRBN (0.46) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL11257635 | 0.79 | CRBN (0.46) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL193400 | 0.77 | CRBN (0.50) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL29125123 | 0.77 | CRBN (0.44) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL6630661 | 0.77 | CRBN (0.44) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL2194813 | 0.77 | CRBN (0.44) | CRBNEPHX2DDB1CYP4F2CYP4A11 | |
| SCHEMBL5826350 | 0.77 | CRBN (0.40) | CRBNEPHX2DDB1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000072837-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROLEPTIC AND RELATED DISORDERS USING SERTINDOLE DERIVATIVES | SEPRACOR INC. (US) | 2000-12-07 | — | — | WO | disclosed |
| EP-0413343-A2 | Furan derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-20 | — | — | EP | disclosed |