Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194067 | 0.87 | CRBN (0.46) | CRBNL3MBTL1TOP2ATOP2BALDH1A1 | |
| SCHEMBL461664 | 0.85 | CRBN (0.45) | CRBNALDH1A1MAPTLMNAPTGS1 | |
| SCHEMBL8716131 | 0.84 | ALOX5 (0.45) | CRBNALDH1A1LMNAPTGS1CYP4F2 | |
| SCHEMBL162839 | 0.84 | ALOX5 (0.45) | CRBNALDH1A1LMNAPTGS1CYP4F2 | |
| SCHEMBL20376257 | 0.84 | ALOX5 (0.45) | CRBNALDH1A1LMNAPTGS1CYP4F2 | |
| SCHEMBL6233217 | 0.84 | ALOX5 (0.45) | CRBNALDH1A1LMNAPTGS1CYP4F2 | |
| SCHEMBL6228568 | 0.84 | ALOX5 (0.45) | CRBNALDH1A1LMNAPTGS1CYP4F2 | |
| SCHEMBL6233785 | 0.84 | ALOX5 (0.45) | CRBNALDH1A1LMNAPTGS1CYP4F2 | |
| SCHEMBL20441211 | 0.84 | ALOX5 (0.45) | CRBNALDH1A1LMNAPTGS1CYP4F2 | |
| SCHEMBL3628533 | 0.84 | ALOX5 (0.45) | CRBNALDH1A1LMNAPTGS1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430442-A | It include the method for handling keratin fiber using the composition comprising urea or derivatives thereof, polyalcohol and amodimethicone | 欧莱雅 | 2018-08-21 | — | — | CN | claimed |
| EP-3601291-B1 | 11,13-MODIFIED SAXITOXINS FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS INC (US) | 2026-05-20 | — | — | EP | disclosed |
| US-12162886-B2 | 11,13-modified saxitoxins for the treatment of pain | SITEONE THERAPEUTICS, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| EP-3639821-B1 | CARCINOGENESIS INHIBITOR | NAT CANCER CT (JP) | 2024-08-28 | — | — | EP | disclosed |
| US-11834456-B2 | 11,13-modified saxitoxins for the treatment of pain | SITEONE THERAPEUTICS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-11834456-B2 | 11,13-modified saxitoxins for the treatment of pain | SITEONE THERAPEUTICS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| EP-3860714-B1 | 11,13-MODIFIED SAXITOXINS FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS INC (US) | 2023-09-06 | — | — | EP | disclosed |
| US-20230259028-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING REACTION PRODUCT OF HYDANTOIN COMPOUNDS | NISSAN CHEMICAL CORPORATION (JP) | 2023-08-17 | — | — | US | disclosed |
| CN-110831945-B | 11, 13-modified saxitoxins for the treatment of pain | 赛特温治疗公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116194211-A | Method and apparatus for producing ammonia | 日产化学株式会社 | 2023-05-30 | — | — | CN | disclosed |
| US-5827717-A | GENE CODING FOR A CARBAMOYLASE, HYDANTOINASE OR HYDANTOIN RACEMASE | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1998-10-27 | — | — | US | disclosed |
| WO-1997043264-A1 | COMPOSITIONS AND METHODS UTILIZING 1,3-BROMOCHLORO-5-METHYL-5-PROPYLHYDANTOIN | GREAT LAKES CHEMICAL CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |
| EP-0780125-A2 | Pharmaceutical composition containing a hydantoin derivative and use of said derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5516660-A | FROM CORRESPONDING HYDANTOINS OR CARBAMOYL AMINO ACIDS;ENZYMATIC CONVERSION IN PRESENCE OF ARTHOBACTER | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| EP-0571904-B1 | Process for preparing methylolhydantoins | LONZA AG (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0571904-A1 | Process for preparing methylolhydantoins | LONZA INC. (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5252744-A | Liquid based methods for the production of solid, anhydrous methylolhydantoins | LONZA INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0358188-A2 | Electrically conductive composition with polyheteroaromates and polymer sulfates | Japat Ltd (CH) | 1990-03-14 | — | — | EP | disclosed |
| US-4537697-A | Method of enhancing solubility of halogenated hydantoins | GLYCO, INC. (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0031996-A1 | Hydantoinylsilanes and bis(hydantoinyl)disiloxanes and method for preparing same | M & T CHEMICALS, INC. (US) | 1981-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834456-B2 | 11,13-modified saxitoxins for the treatment of pain | SCN11A, SCN10A, CACNA1A | CRBN 3204/4885L3MBTL1 3602/4885TOP2A 3569/4885 |
| US-12162886-B2 | 11,13-modified saxitoxins for the treatment of pain | SCN11A, SCN10A, SCN3A | CRBN 4496/4885L3MBTL1 4079/4885TOP2A 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.