SCHEMBL8029533

SCHEMBL8029533

C=CC(=O)Nc1ccc2oc(C)nc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.65
NPC1 O15118 5/20 0.65
SMN1; SMN2 Q16637 4/20 0.65
STAT1 P42224 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
KDM4E B2RXH2 4/20 0.62
MAPT P10636 3/20 0.62
POLB P06746 3/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
PPARG P37231 1/20 0.62
LMNA P02545 3/20 0.60
GAA P10253 3/20 0.58
ALDH1A1 P00352 2/20 0.58
PKM P14618 1/20 0.58
MAPK1 P28482 2/20 0.53
TP53 P04637 2/20 0.53
HSD17B10 Q99714 2/20 0.53
EPHX2 P34913 1/20 0.51
TGM2 P21980 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30191228 0.86 PPARG (0.54) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL24150636 0.86 PPARG (0.54) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL2490209 0.82 RAB9A (0.72) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL17371305 0.77 RAB9A (0.53) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL27188294 0.77 PPARG (1.00) RAB9ANPC1SMN1; SMN2KDM4EMAPT
SCHEMBL25598114 0.76 PPARG (0.52) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL12349876 0.75 RAB9A (0.57) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL24449257 0.74 KDM4E (0.71) RAB9ANPC1SMN1; SMN2L3MBTL1KDM4E
SCHEMBL3958735 0.74 RAB9A (0.74) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1
SCHEMBL8019090 0.74 RAB9A (0.69) RAB9ANPC1SMN1; SMN2STAT1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0561475-B1 Bleachable polymeric filter dyes EASTMAN KODAK CO (US) 2000-03-01 EP disclosed
EP-0561475-A1 Bleachable polymeric filter dyes EASTMAN KODAK COMPANY (US) 1993-09-22 EP disclosed
US-5244994-A Benzoxazole styryl chromophore attached to polymer, X-ray films, high speed EASTMAN KODAK COMPANY (US) 1993-09-14 US disclosed