Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042725 | 0.87 | SIRT2 (0.35) | DPP4SIRT2SIRT1F2F10 | |
| SCHEMBL8029685 | 0.87 | SIRT2 (0.35) | DPP4SIRT2SIRT1F2F10 | |
| SCHEMBL8029146 | 0.87 | SIRT2 (0.35) | DPP4SIRT2SIRT1F2F10 | |
| SCHEMBL7417913 | 0.87 | SIRT2 (0.35) | DPP4SIRT2SIRT1F2F10 | |
| SCHEMBL8039170 | 0.83 | HCRTR1 (0.41) | HCRTR1HCRTR2GPR6DPP4KDM1A | |
| Hydrochloric Acid SCHEMBL8029623 | 0.82 | HCRTR1 (0.41) | HCRTR1HCRTR2GPR6DPP4KDM1A | |
| Hydrochloric Acid SCHEMBL7420338 | 0.82 | HCRTR1 (0.41) | HCRTR1HCRTR2GPR6DPP4KDM1A | |
| SCHEMBL7424934 | 0.81 | FNTA (0.44) | DPP4 | |
| SCHEMBL8833260 | 0.79 | SIRT2 (0.55) | MGLLDPP4SIRT2SIRT1HSD11B1 | |
| SCHEMBL7419118 | 0.79 | SIRT2 (0.55) | MGLLDPP4SIRT2SIRT1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034093-A | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-03-07 | — | — | US | disclosed |