Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112513 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL110651 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL112512 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL5220076 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL109917 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL5366842 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL112307 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL110652 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL114444 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C | |
| SCHEMBL114445 | 1.00 | NAAA (0.50) | NAAAEPHX1NOD1TSHRHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143275-A | BIFUNCTIONAL CHELATING AGENTS WITH INTERMITTENT CHALCOGEN ATOMS FOR USE IN RADIODIAGNOSTICS AND RADIOTHERAPY | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2000-11-07 | — | — | US | disclosed |
| US-5961954-A | Chealators of type XN1 S1 X1 for radioactive isotopes, their metal complexes and their diagnostic and therapeutical uses | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 1999-10-05 | — | — | US | disclosed |
| US-4279900-A | ANTIINFLAMMATORY | INTREX RESEARCH CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
| US-4268441-A | Prodrugs for improved bioavailability of certain Δ4 -3-ketosteroidal sex hormones | INTERX RESEARCH CORPORATION (US) | 1981-05-19 | — | — | US | disclosed |
| US-4239757-A | Thiazolidine prodrugs for the improved delivery of anti-inflammatory corticosteroids | INTERX RESEARCH CORPORATION (US) | 1980-12-16 | — | — | US | disclosed |
| US-4213978-A | Anti-acne and anti-seborrhea prodrug derivatives of progesterone | INTERX RESEARCH CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |