SCHEMBL5220076

SCHEMBL5220076

CCCCCCCCCCCCCCCCOC(=O)[C@@H](N)CS

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.50
EPHX1 P07099 1/20 0.47
NOD1 Q9Y239 2/20 0.47
TSHR P16473 3/20 0.46
HTR2C P28335 1/20 0.45
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
HCAR2 Q8TDS4 1/20 0.43
RAD52 P43351 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 2/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
FAAH O00519 1/20 0.42
LMNA P02545 1/20 0.42
ACHE P22303 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112513 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL110651 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL112512 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL8029779 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL109917 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL5366842 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL112307 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL110652 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL114444 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C
SCHEMBL114445 1.00 NAAA (0.50) NAAAEPHX1NOD1TSHRHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101568350-B Lipidized interferon and uses thereof SHEN WEIQIANG 2013-11-06 CN claimed
CN-101568350-A Lipidized interferon and uses thereof SHEN WEI CHIANG (US) 2009-10-28 CN claimed
US-20240141017-A1 FLUORESCENT BIOSENSORS AND METHODS OF USE FOR DETECTING CELL SIGNALING EVENTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-05-02 US disclosed
EP-4298443-A1 FLUORESCENT BIOSENSORS AND METHODS OF USE FOR DETECTING CELL SIGNALING EVENTS The Regents Of The University Of Michigan (US) 2024-01-03 EP disclosed
WO-2022182932-A1 FLUORESCENT BIOSENSORS AND METHODS OF USE FOR DETECTING CELL SIGNALING EVENTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-09-01 WO disclosed
CN-108430993-A TANK-BINDING KINASE INHIBITOR COMPOUNDS 吉利德科学公司 2018-08-21 CN disclosed
US-20170283455-A1 STABLE TOPICAL PHAMACEUTICAL COMPOSITIONS OF HALOBETASOL PROPIONATE SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2017-10-05 US disclosed
CN-106237316-A The compositions comprising hemagglutinin, the method manufacturing it and the method using it 法克斯因内特公司 2016-12-21 CN disclosed
CN-101568350-B Lipidized interferon and uses thereof SHEN WEIQIANG 2013-11-06 CN disclosed
CN-101568350-A Lipidized interferon and uses thereof SHEN WEI CHIANG (US) 2009-10-28 CN disclosed
CN-101405401-A Genetic programming expression of protein containing unnatural amino acid phenylselenocysteine SCRIPPS RESEARCH INST (US) 2009-04-08 CN disclosed
EP-1575900-A4 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LT (AU) 2007-02-21 EP disclosed
CN-1791675-A Viral vectors expressing fusion of viral large envelope protein and protein of interest HEPGENICS PTY LTD (AU) 2006-06-21 CN disclosed
EP-1575900-A1 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LTD (AU) 2005-09-21 EP disclosed
CN-1192101-C Production of the lipidated form of the peptido glycon-associated lipoproteins of gram-negative bacteria WYETH CORP (US) 2005-03-09 CN disclosed
WO-2004007427-A1 N-METHYL AMINO ACIDS UBIQUITOUS TECHNOLOGIES PTY LTD (AU) 2004-01-22 WO disclosed
CN-1358227-A Preparation of lipidated forms of peptidoglycan-binding lipoproteins of gram-negative bacteria AMERICAN CYANAMID CO (US) 2002-07-10 CN disclosed
CN-1244126-A Universal T-cell epitopes for anti-malarial vaccines UNIV NEW YORK (US) 2000-02-09 CN disclosed
US-5632982-A Cytotoxic enhancement of TNF with copper THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-05-27 US disclosed
EP-0080944-A1 Cephalosporin derivatives substituted in position 3 with a thiomethylheterocyclic group, process for their preparation and pharmaceutical compositions containing them SANOFI S.A. (FR) 1983-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170283455-A1 STABLE TOPICAL PHAMACEUTICAL COMPOSITIONS OF HALOBETASOL PROPIONATE CYP8B1, CYP51A1, HSD17B7 NAAA 3498/4885EPHX1 812/4885NOD1 4615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.