Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020433 | 0.86 | TDP1 (0.50) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL6640405 | 0.76 | TDP1 (0.62) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL6961763 | 0.76 | TDP1 (0.49) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL10045566 | 0.76 | TDP1 (0.49) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL4922982 | 0.75 | TDP1 (0.60) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL6576203 | 0.75 | TDP1 (0.60) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL6646572 | 0.75 | TDP1 (0.60) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL5042301 | 0.72 | TDP1 (0.56) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL31514206 | 0.72 | TDP1 (0.56) | TDP1MAPK1TSHRVCAM1ALDH1A1 | |
| SCHEMBL5035521 | 0.71 | TDP1 (0.55) | TDP1MAPK1TSHRVCAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069435-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-11-23 | — | — | WO | disclosed |