SCHEMBL6640405

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL278504	0.85	TDP1 (0.62)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL6576203	0.83	TDP1 (0.60)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL4922982	0.83	TDP1 (0.60)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL6646572	0.83	TDP1 (0.60)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL5042301	0.80	TDP1 (0.56)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL31514206	0.80	TDP1 (0.56)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL5035521	0.79	TDP1 (0.55)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL278488	0.77	TDP1 (1.00)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL29975243	0.77	ALDH1A1 (0.53)	TDP1TSHRMAPK1ALDH1A1
	SCHEMBL10756135	0.77	ALDH1A1 (0.53)	TDP1TSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.