Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18231450 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1BEPHX2DRD2DRD3 | |
| SCHEMBL7262280 | 0.73 | SLC18A3 (0.39) | MTNR1AMTNR1BEPHX2CHRM2CHRM1 | |
| SCHEMBL7258685 | 0.72 | MTNR1A (0.39) | MTNR1AMTNR1BEPHX2CYP1A2MAPT | |
| SCHEMBL472441 | 0.72 | MTNR1A (0.39) | MTNR1AMTNR1BEPHX2DRD2HTR1D | |
| SCHEMBL472439 | 0.72 | MTNR1A (0.39) | MTNR1AMTNR1BEPHX2DRD2HTR1D | |
| SCHEMBL4427467 | 0.72 | ACHE (0.62) | DRD2DRD3CHRM2CHRM1CHRM3 | |
| SCHEMBL23045107 | 0.71 | MTNR1A (0.46) | MTNR1AMTNR1BEPHX2CYP1A2MAPT | |
| SCHEMBL23045109 | 0.71 | MTNR1A (0.46) | MTNR1AMTNR1BEPHX2CYP1A2MAPT | |
| SCHEMBL345918 | 0.70 | CYP1A2 (0.62) | MTNR1AMTNR1BEPHX2CYP1A2MAPT | |
| SCHEMBL8080856 | 0.70 | CYP1A2 (0.62) | MTNR1AMTNR1BEPHX2CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000077027-A2 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2000-12-21 | — | — | WO | disclosed |