Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376637 | 0.87 | THRB (0.48) | KMT2AALDH1A1MEN1HTTKDM4E | |
| SCHEMBL8036800 | 0.80 | ALDH1A1 (0.53) | KMT2AALDH1A1MEN1HTTKDM4E | |
| SCHEMBL1613946 | 0.79 | ALDH1A1 (0.74) | KMT2AALDH1A1MEN1HTTKDM4E | |
| SCHEMBL11511969 | 0.79 | ALDH1A1 (0.62) | KMT2AALDH1A1MEN1HTTKDM4E | |
| SCHEMBL1146176 | 0.78 | ALDH1A1 (0.72) | KMT2AALDH1A1MEN1HTTKDM4E | |
| SCHEMBL8020586 | 0.77 | KMT2A (0.55) | KMT2AALDH1A1MEN1HTTKDM4E | |
| SCHEMBL13099833 | 0.76 | KDM4E (0.65) | KMT2AALDH1A1MEN1HTTKDM4E | |
| SCHEMBL30581469 | 0.76 | KDM4E (0.65) | KMT2AALDH1A1MEN1HTTKDM4E | |
| SCHEMBL1016036 | 0.76 | ALDH1A1 (0.61) | KMT2AALDH1A1MEN1LMNANPC1 | |
| SCHEMBL12309435 | 0.76 | ALDH1A1 (0.68) | KMT2AALDH1A1MEN1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5919824-A | Aminophenol derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |