Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.79 |
| ▸ | TYR | P14679 | 2/20 | 0.79 |
| ▸ | BCHE | P06276 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Trans-Feruloyl Tyramine SCHEMBL29477339 | 0.93 | TYR (0.83) | ACHETYRBCHEHDAC1HDAC6 | |
| N-Trans-Feruloyl Tyramine SCHEMBL17693085 | 0.93 | TYR (0.83) | ACHETYRBCHEHDAC1HDAC6 | |
| N-Trans-Feruloyl Tyramine SCHEMBL30069091 | 0.93 | TYR (0.83) | ACHETYRBCHEHDAC1HDAC6 | |
| N-Trans-Feruloyl Tyramine SCHEMBL2378679 | 0.93 | TYR (0.83) | ACHETYRBCHEHDAC1HDAC6 | |
| N-Trans-Feruloyl Tyramine SCHEMBL1675910 | 0.93 | TYR (0.83) | ACHETYRBCHEHDAC1HDAC6 | |
| SCHEMBL1917145 | 0.93 | TYR (0.91) | ACHETYRMAPTHDAC1HDAC6 | |
| SCHEMBL1842826 | 0.93 | TYR (0.91) | ACHETYRMAPTHDAC1HDAC6 | |
| SCHEMBL29363766 | 0.93 | TYR (0.91) | ACHETYRMAPTHDAC1HDAC6 | |
| SCHEMBL4812187 | 0.93 | TYR (0.91) | ACHETYRMAPTHDAC1HDAC6 | |
| SCHEMBL31252895 | 0.93 | TYR (0.91) | ACHETYRMAPTHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295624-B2 | Amide derivative and whitening agent | AJINOMOTO CO., INC. (JP) | 2016-03-29 | — | — | US | disclosed |
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2412701-A1 | NOVEL AMIDE DERIVATIVE AND SKIN WHITENING AGENT | Ajinomoto Co., Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | ACHE 291/4885TYR 3/4885BCHE 965/4885 |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | ACHE 291/4885TYR 3/4885BCHE 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.