Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.83 |
| ▸ | ACHE | P22303 | 2/20 | 0.83 |
| ▸ | CNR2 | P34972 | 2/20 | 0.71 |
| ▸ | MAOA | P21397 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.69 |
| ▸ | MET | P08581 | 2/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA4 | P22748 | 1/20 | 0.67 |
| ▸ | CA6 | P23280 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Trans-Feruloyl Tyramine SCHEMBL2378679 | 1.00 | TYR (0.83) | TYRACHECNR2MAOAMAOB | |
| N-Trans-Feruloyl Tyramine SCHEMBL1675910 | 1.00 | TYR (0.83) | TYRACHECNR2MAOAMAOB | |
| N-Trans-Feruloyl Tyramine SCHEMBL29477339 | 1.00 | TYR (0.83) | TYRACHECNR2MAOAMAOB | |
| N-Trans-Feruloyl Tyramine SCHEMBL30069091 | 1.00 | TYR (0.83) | TYRACHECNR2MAOAMAOB | |
| SCHEMBL17327985 | 0.93 | TYR (0.78) | TYRACHECNR2MAOAMAOB | |
| SCHEMBL802998 | 0.93 | ACHE (0.79) | TYRACHEMAOAMAOBBCHE | |
| SCHEMBL4812187 | 0.93 | TYR (0.91) | TYRACHEMAOAMAOBMET | |
| SCHEMBL1842826 | 0.93 | TYR (0.91) | TYRACHEMAOAMAOBMET | |
| SCHEMBL31252895 | 0.93 | TYR (0.91) | TYRACHEMAOAMAOBMET | |
| SCHEMBL1917145 | 0.93 | TYR (0.91) | TYRACHEMAOAMAOBMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114146104-A | Anti-inflammatory active extract of achyranthes aspera | 湖南时代阳光药业股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-110613741-B | Anti-inflammatory active extract of achyranthes aspera and preparation method thereof | 湖南时代阳光药业股份有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-120858857-B | Application of N-cis feruloyl tyramine in improving rice alkali stress tolerance | 三亚市国家耐盐碱水稻技术创新中心 | 2026-01-06 | — | — | CN | disclosed |
| CN-120858857-A | Application of N-cis feruloyl tyramine in improving rice alkali stress tolerance | 三亚市国家耐盐碱水稻技术创新中心 | 2025-10-31 | — | — | CN | disclosed |
| EP-4590287-A1 | COMPOSITIONS AND METHODS FOR IMPROVING GUT PERMEABILITY | Brightseed, Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| CN-114306550-B | Traditional Chinese medicine formula for regulating and controlling intestinal functions of perimenopausal women | 刘敏如女科医系研究院(深圳)有限公司 | 2024-09-17 | — | — | CN | disclosed |
| WO-2024064102-A1 | COMPOSITIONS AND METHODS FOR IMPROVING GUT PERMEABILITY | BRIGHTSEED, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2023287620-A9 | METHODS FOR TREATING CORONAVIRUS INFECTION | RABINOFF MICHAEL (US) | 2023-11-30 | — | — | WO | disclosed |
| US-20230354864-A1 | EXTRACT, CONSUMABLE PRODUCT AND METHOD FOR ENRICHING BIOACTIVE METABOLITE IN AN EXTRACT | BRIGHTSEED, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230354864-A1 | EXTRACT, CONSUMABLE PRODUCT AND METHOD FOR ENRICHING BIOACTIVE METABOLITE IN AN EXTRACT | BRIGHTSEED, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230270699-A1 | METHOD FOR MODULATING METABOLISM | Sanford Burnham Prebys Medical Discovery Institute | 2023-08-31 | — | — | US | disclosed |
| US-20170105975-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-04-20 | — | — | US | disclosed |
| US-20170042865-A1 | THERAPEUTIC COMPOSITIONS CONTAINING CURCUMIN, HARMINE, AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-02-16 | — | — | US | disclosed |
| US-20170042867-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-02-16 | — | — | US | disclosed |
| US-20170042866-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-02-16 | — | — | US | disclosed |
| US-9402834-B2 | Human therapeutic agents | IONS PHARMACEUTICAL S.À R.L. (LU) | 2016-08-02 | — | — | US | disclosed |
| US-20160106687-A1 | HUMAN THERAPEUTIC AGENTS | IONS PHARMACEUTICAL S.À R.L. (LU) | 2016-04-21 | — | — | US | disclosed |
| US-20160106724-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2016-04-21 | — | — | US | disclosed |
| US-20160106721-A1 | HUMAN THERAPEUTIC AGENTS | IONS PHARMACEUTICAL S.À R.L. (LU) | 2016-04-21 | — | — | US | disclosed |
| US-20160106722-A1 | HUMAN THERAPEUTIC AGENTS | IONS PHARMACEUTICAL S.À R.L. (LU) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230354864-A1 | EXTRACT, CONSUMABLE PRODUCT AND METHOD FOR ENRICHING BIOACTIVE METABOLITE IN AN EXTRACT | HCAR2, HNMT, TYR | TYR 3/4885ACHE 370/4885CNR2 612/4885 |
| US-20230270699-A1 | METHOD FOR MODULATING METABOLISM | GOT2, GYS2, PC | TYR 1959/4885ACHE 1275/4885CNR2 1156/4885 |
| US-20170042865-A1 | THERAPEUTIC COMPOSITIONS CONTAINING CURCUMIN, HARMINE, AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, CPT1A | TYR 84/4885ACHE 478/4885CNR2 654/4885 |
| US-20170042867-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | TYR 51/4885ACHE 605/4885CNR2 280/4885 |
| US-20170042866-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | TYR 51/4885ACHE 605/4885CNR2 280/4885 |
| US-20160106722-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | TYR 189/4885ACHE 2039/4885CNR2 586/4885 |
| US-20170105975-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | TYR 51/4885ACHE 605/4885CNR2 280/4885 |
| US-20160106721-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | TYR 189/4885ACHE 2039/4885CNR2 586/4885 |
| US-20160106724-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | TYR 189/4885ACHE 2039/4885CNR2 586/4885 |
| US-20160106687-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | TYR 189/4885ACHE 2039/4885CNR2 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.