Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398865 | 1.00 | MEN1 (0.44) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL8030151 | 1.00 | MEN1 (0.44) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL1658450 | 0.86 | MEN1 (0.56) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL261024 | 0.86 | MEN1 (0.56) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL10832031 | 0.84 | MEN1 (0.55) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7900597 | 0.84 | MEN1 (0.55) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7900601 | 0.84 | MEN1 (0.55) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL8031948 | 0.84 | SIGMAR1 (0.37) | GRIA1GRIA2GRIA3USP30HRH3 | |
| SCHEMBL8031953 | 0.84 | SIGMAR1 (0.37) | GRIA1GRIA2GRIA3USP30HRH3 | |
| SCHEMBL8031956 | 0.84 | SIGMAR1 (0.37) | GRIA1GRIA2GRIA3USP30HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718301-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0630903-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5679746-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0718301-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5454977-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-03 | — | — | US | disclosed |
| EP-0630903-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |