Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | IAPP | P10997 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933913 | 0.90 | GAA (0.40) | CA2IAPPGAAKMT2AMEN1 | |
| SCHEMBL7941106 | 0.86 | IAPP (0.42) | CA2IAPPGAAGABRA1GABRB2 | |
| SCHEMBL7944740 | 0.81 | GAA (0.48) | CA2IAPPGAAGABRA1GABRB2 | |
| SCHEMBL7944861 | 0.80 | GAA (0.44) | GAAKMT2AATMMEN1ALDH1A1 | |
| SCHEMBL7933847 | 0.80 | HSPA5 (0.51) | CA2GAAKMT2AATMMEN1 | |
| SCHEMBL7933754 | 0.79 | GAA (0.46) | CA2IAPPGAAKMT2AMEN1 | |
| SCHEMBL4975584 | 0.78 | CA2 (0.52) | CA2IAPPGABRA1GABRB2ATM | |
| SCHEMBL30501159 | 0.78 | CA2 (0.52) | CA2IAPPGABRA1GABRB2ATM | |
| SCHEMBL7941452 | 0.78 | GAA (0.45) | CA2IAPPGAAKMT2AMEN1 | |
| SCHEMBL3809080 | 0.77 | CA2 (0.59) | CA2IAPPGABRA1GABRB2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075159-A | USE AS A STABILIZER FOR AN ORGANIC MATERIAL SUCH AS THERMOPLASTIC RESINS, THERMOSETTING RESINS, NATURAL OR SYNTHETIC RUBBERS, MINERAL OILS, LUBRICATING OILS, ADHESIVES AND PAINTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-13 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |