Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030249 | 0.90 | CA2 (0.42) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL8018921 | 0.81 | LMNA (0.49) | GAALMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7941106 | 0.77 | IAPP (0.42) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL7944861 | 0.77 | GAA (0.44) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL7933847 | 0.77 | HSPA5 (0.51) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL7933918 | 0.76 | GAA (0.67) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL7944869 | 0.73 | CYP1A2 (0.45) | GAALMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7933901 | 0.73 | CA2 (0.48) | GAAALDH1A1ALOX5PTGS1PTGS2 | |
| SCHEMBL7944740 | 0.73 | GAA (0.48) | GAAKMT2ACA2MEN1MAOB | |
| SCHEMBL10427578 | 0.72 | CA2 (0.52) | GAALMNAALDH1A1PTGS1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |