Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029961 | 0.95 | KMT2A (0.38) | KMT2AMEN1GAABDKRB2NPSR1 | |
| SCHEMBL27488423 | 0.94 | KMT2A (0.35) | KMT2AMEN1GAABDKRB2NPSR1 | |
| SCHEMBL8020589 | 0.92 | SMN1; SMN2 (0.35) | KMT2AMEN1GAABDKRB2NPSR1 | |
| SCHEMBL8029577 | 0.92 | KMT2A (0.40) | KMT2AMEN1GAABDKRB2NPSR1 | |
| SCHEMBL8031924 | 0.91 | KMT2A (0.35) | KMT2AMEN1GAABDKRB2HTT | |
| SCHEMBL8032250 | 0.90 | KMT2A (0.38) | KMT2AMEN1GAANPSR1HTT | |
| SCHEMBL8030267 | 0.89 | KMT2A (0.42) | KMT2AMEN1GAABDKRB2NPSR1 | |
| SCHEMBL8029983 | 0.89 | SMN1; SMN2 (0.36) | KMT2AMEN1GAANPSR1HTT | |
| SCHEMBL8033942 | 0.89 | KMT2A (0.40) | KMT2AMEN1HTTSMN1; SMN2MAPK1 | |
| SCHEMBL8036207 | 0.89 | GRM5 (0.38) | KMT2AMEN1GAANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |