Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020589 | 0.94 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2AMEN1PPIBHTT | |
| SCHEMBL8020901 | 0.94 | SMN1; SMN2 (0.37) | SMN1; SMN2KMT2AMEN1PPIBHTT | |
| SCHEMBL8031924 | 0.93 | KMT2A (0.35) | SMN1; SMN2KMT2AMEN1PPIBHTT | |
| SCHEMBL8033942 | 0.92 | KMT2A (0.40) | SMN1; SMN2KMT2AMEN1HTTNPC1 | |
| SCHEMBL8036207 | 0.92 | GRM5 (0.38) | SMN1; SMN2KMT2AMEN1PPIBHTT | |
| SCHEMBL8030634 | 0.91 | KMT2A (0.36) | SMN1; SMN2KMT2AMEN1PPIBHTT | |
| SCHEMBL8020564 | 0.90 | KDM4E (0.37) | SMN1; SMN2KMT2AMEN1PPIBHTT | |
| SCHEMBL8030465 | 0.89 | KMT2A (0.38) | SMN1; SMN2KMT2AMEN1HTTNPC1 | |
| SCHEMBL8030377 | 0.89 | KMT2A (0.39) | SMN1; SMN2KMT2AMEN1PPIBHTT | |
| SCHEMBL8020806 | 0.88 | POLQ (0.37) | SMN1; SMN2KMT2AMEN1PPIBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |