Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033942 | 0.95 | KMT2A (0.40) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8020806 | 0.94 | POLQ (0.37) | GRM5PPIBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8031868 | 0.94 | PPIB (0.38) | GRM5PPIBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8029983 | 0.92 | SMN1; SMN2 (0.36) | PPIBALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8020589 | 0.91 | SMN1; SMN2 (0.35) | PPIBALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8030634 | 0.91 | KMT2A (0.36) | PPIBALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8020564 | 0.90 | KDM4E (0.37) | PPIBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8031924 | 0.90 | KMT2A (0.35) | PPIBALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8036317 | 0.90 | MAPK1 (0.45) | PPIBSMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL8031875 | 0.89 | MAPK1 (0.40) | SMN1; SMN2KMT2AMEN1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |