Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 6/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804927 | 0.84 | FDPS (0.33) | FDPSGHSRCHRNB4CHRNA3MEN1 | |
| SCHEMBL27426206 | 0.83 | FDPS (0.37) | FDPSGHSRCHRNB4CHRNA3MEN1 | |
| SCHEMBL710155 | 0.83 | FDPS (0.37) | FDPSGHSRCHRNB4CHRNA3MEN1 | |
| Hydrochloric Acid SCHEMBL6597987 | 0.82 | FDPS (0.36) | FDPSGHSRCHRNB4CHRNA3MEN1 | |
| SCHEMBL5970476 | 0.74 | CHRNB4 (0.38) | FDPSCHRNB4CHRNA3 | |
| SCHEMBL5970473 | 0.74 | CHRNB4 (0.38) | FDPSCHRNB4CHRNA3 | |
| SCHEMBL28124595 | 0.74 | OPRM1 (0.35) | FDPSLMNACYP3A4SMN1; SMN2NPSR1 | |
| SCHEMBL79825 | 0.73 | EPHX1 (0.44) | MEN1LMNACYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL145280 | 0.73 | EPHX1 (0.44) | MEN1LMNACYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL1268688 | 0.73 | EPHX1 (0.44) | MEN1LMNACYP3A4KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981539-A1 | DOLASTATIN 15 DERIVATIVES WITH CARBONYL AND HETEROCYCLIC FUNCTIONALITIES AT THE C-TERMINUS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-01 | — | — | EP | disclosed |
| US-5965537-A | ANTICANCER AGENTS; WATER SOLUBILITY | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | disclosed |
| WO-1998040400-A1 | DOLASTATIN 15 DERIVATIVES WITH CARBONYL AND HETEROCYCLIC FUNCTIONALITIES AT THE C-TERMINUS | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |