SCHEMBL8030650

SCHEMBL8030650

COC(=O)c1ccc(N)cc1S(N)(=O)=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.67
CA2 P00918 6/20 0.65
CA1 P00915 4/20 0.65
CA9 Q16790 4/20 0.65
CA5A P35218 1/20 0.65
ALDH1A1 P00352 6/20 0.49
HSD17B10 Q99714 4/20 0.49
KDM4E B2RXH2 4/20 0.49
MAPT P10636 3/20 0.49
HPGD P15428 2/20 0.49
GLA P06280 1/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
ATM Q13315 1/20 0.49
ABL1 P00519 1/20 0.47
CA12 O43570 3/20 0.47
CA14 Q9ULX7 3/20 0.47
CA7 P43166 2/20 0.47
PDK2 Q15119 1/20 0.47
PDK4 Q16654 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14687567 0.88 GAA (0.60) GAACA2CA1CA9CA5A
SCHEMBL11226378 0.88 CA2 (0.63) GAACA2CA1CA9CA5A
SCHEMBL30827404 0.88 CA2 (0.63) GAACA2CA1CA9CA5A
SCHEMBL22010624 0.85 CA2 (0.63) GAACA2CA1CA9CA5A
SCHEMBL11372105 0.85 CA1 (0.63) GAACA2CA1CA9CA5A
SCHEMBL29452074 0.84 GAA (0.55) GAACA2CA1CA9CA5A
SCHEMBL8034737 0.83 CA2 (0.61) GAACA2CA1CA9CA5A
SCHEMBL21962924 0.83 CA2 (0.61) GAACA2CA1CA9CA5A
SCHEMBL21962894 0.83 CA2 (0.61) GAACA2CA1CA9CA5A
SCHEMBL9826218 0.83 CA2 (0.61) GAACA2CA1CA9CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101768093-A Preparation method of 2-carbomethoxy-5-iodobenzene sulfamide JIANGSU AGROCHEM LAB ENGINEERI 2010-07-07 CN claimed
WO-2018104305-A1 FIELD OF APPLICATION OF THE INVENTION BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-06-14 WO disclosed
CN-101768093-A Preparation method of 2-carbomethoxy-5-iodobenzene sulfamide JIANGSU AGROCHEM LAB ENGINEERI 2010-07-07 CN disclosed
CN-101768093-A Preparation method of 2-carbomethoxy-5-iodobenzene sulfamide JIANGSU AGROCHEM LAB ENGINEERI 2010-07-07 CN disclosed
US-6147248-A 4-jod-2[N-(N-alkyl-aminocarbonyl)-aminosulfonyl]-benzoic acid methyl ester and derivatived thereof and method for their production HOECHST SCHERING AGREVO GMBH (DE) 2000-11-14 US disclosed
EP-0562575-B1 N-substituted-3-(substituted hydrazino)-benzenesulfonamide derivative, preparation process thereof, and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1998-09-16 EP disclosed
EP-0382437-B1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1995-08-16 EP disclosed
EP-0382436-B1 N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1995-05-10 EP disclosed
US-5362885-A Herbicides KUREHA KAGAKU KOGYO K.K. (JP) 1994-11-08 US disclosed
EP-0562575-A2 N-substituted-3-(substited hydrazino)-benzenesulfonamide derivatives, prepation process thereof, and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-09-29 EP disclosed
US-5242894-A N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, and herbicidal compositions KUREHA KAGAKU KOGYO K.K. (JP) 1993-09-07 US disclosed
US-5198566-A N-substituted-3-(substituted hydrazino)-benzenesulfonamides KUREHA KAGAKU KOGYO K.K. (JP) 1993-03-30 US disclosed
US-5151114-A Applying to weeds ARAHORI HIDEO (JP) 1992-09-29 US disclosed
US-5127937-A N-SUBSTITUTED-3-(NITROGEN-CONTAINING 5-MEMBERED RING)-BENZENESULFONAMIDE DERIVATIVES, AND HERBICIDAL COMPOSITIONS KUREHA KAGAKU KOGYO K.K. (JP) 1992-07-07 US disclosed
US-5059238-A Controlling mono- and dicotyledons KUREHA KAGAKU KOGYO K.K. (JP) 1991-10-22 US disclosed
EP-0382436-A1 N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP disclosed
EP-0382437-A1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP disclosed