SCHEMBL8034737

SCHEMBL8034737

COC(=O)c1ccc(I)cc1S(N)(=O)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.61
CA1 P00915 4/20 0.61
CA9 Q16790 4/20 0.61
CA5A P35218 1/20 0.61
GAA P10253 2/20 0.50
CA12 O43570 3/20 0.45
CA14 Q9ULX7 3/20 0.45
CA7 P43166 2/20 0.45
PDK2 Q15119 1/20 0.45
PDK4 Q16654 1/20 0.45
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
GLA P06280 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
ATM Q13315 1/20 0.42
ABL1 P00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9143218 0.87 CA2 (0.61) CA2CA1CA9CA5AGAA
SCHEMBL8668287 0.85 CA2 (0.46) CA2CA1CA9CA5AGAA
SCHEMBL5930965 0.84 CA2 (0.45) CA2CA1CA9CA5AGAA
SCHEMBL8030650 0.83 GAA (0.67) CA2CA1CA9CA5AGAA
SCHEMBL28090844 0.83 CA1 (0.52) CA2CA1CA9CA5ACA12
SCHEMBL11372105 0.82 CA1 (0.63) CA2CA1CA9CA5AGAA
SCHEMBL22010624 0.82 CA2 (0.63) CA2CA1CA9CA5AGAA
SCHEMBL8030682 0.82 CA2 (0.44) CA2CA1CA9CA5AGAA
SCHEMBL27620079 0.81 CA1 (0.40) CA2CA1CA9CA5AGAA
SCHEMBL21962894 0.81 CA2 (0.61) CA2CA1CA9CA5AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103936684-B Sulfoamido carbonyl triazole quinoline ketonic compound and its preparation method and application 江苏省农用激素工程技术研究中心有限公司 2016-10-05 CN claimed
CN-101768093-A Preparation method of 2-carbomethoxy-5-iodobenzene sulfamide JIANGSU AGROCHEM LAB ENGINEERI 2010-07-07 CN claimed
CN-116554116-A Synthesis method of methyl iodosulfuron 江苏省农用激素工程技术研究中心有限公司 2023-08-08 CN disclosed
CN-110156714-A The preparation method of iodosulfuron methyl sodium intermediate 江苏省农用激素工程技术研究中心有限公司 2019-08-23 CN disclosed
US-10059676-B2 Process for preparing a novel crystalline form of iodosulfuron-methyl-sodium and use of the same ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2018-08-28 US disclosed
US-9700053-B2 Synergistic herbicidal composition and use thereof ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-07-11 US disclosed
US-20170121294-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF IODOSULFURON-METHYL-SODIUM AND USE OF THE SAME ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-05-04 US disclosed
US-20170121294-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF IODOSULFURON-METHYL-SODIUM AND USE OF THE SAME ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-05-04 US disclosed
US-20170121294-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF IODOSULFURON-METHYL-SODIUM AND USE OF THE SAME ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-05-04 US disclosed
WO-2017071408-A1 A SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF JIANGSU ROTAM CHEMISTRY CO., LTD (CN) 2017-05-04 WO disclosed
WO-2017071410-A1 PROCESS FOR PREPARING NOVEL CRYSTALLINE FORM OF IODOSULFURON-METHYL-SODIUM AND USE ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-05-04 WO disclosed
CN-1071748-C Method of preparing sulphonyl ureas with herbicidal properties and N-pyrimidinyl or N-triazinyl carbamates as intermediates in the reaction HOECHST SCHERING AGREVO GMBH (DE) 2001-09-26 CN disclosed
US-6147248-A 4-jod-2[N-(N-alkyl-aminocarbonyl)-aminosulfonyl]-benzoic acid methyl ester and derivatived thereof and method for their production HOECHST SCHERING AGREVO GMBH (DE) 2000-11-14 US disclosed
US-5936085-A Process for the preparation of herbicidal sulfonylureas and of N-(pyrimidinyl or triazinyl)-carbamates as intermediate products HOECHST SCHERING AGREVO GMBH (DE) 1999-08-10 US disclosed
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP disclosed
CN-1192210-A Method of preparing sulphonyl ureas with herbicidal properties and N-pyrimidinyl or N-triazinyl carbamates as intermediates in the reaction HOECHST SCHERING AGREVO GMBH (DE) 1998-09-02 CN disclosed
US-5688745-A Arylsulfonylureas and their use as herbicides and growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170121294-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF IODOSULFURON-METHYL-SODIUM AND USE OF THE SAME SCLY, STS, MPST CA2 701/4885CA1 355/4885CA9 102/4885
US-10059676-B2 Process for preparing a novel crystalline form of iodosulfuron-methyl-sodium and use of the same SCLY, STS, MPST CA2 701/4885CA1 355/4885CA9 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.