Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 8/20 | 0.55 |
| ▸ | ACE | P12821 | 8/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030684 | 0.95 | MME (0.62) | TACR1MMEACECTSLCTSB | |
| SCHEMBL27464503 | 0.88 | TACR1 (0.57) | TACR1MMEACECTSLCTSB | |
| SCHEMBL8016973 | 0.88 | MME (0.53) | MMEACECTSLCTSBCTSS | |
| SCHEMBL27464097 | 0.88 | ACE (0.52) | TACR1MMEACECTSBCPA1 | |
| SCHEMBL27464504 | 0.85 | ACE (0.60) | TACR1MMEACECTSLCTSB | |
| SCHEMBL8027283 | 0.84 | MME (0.75) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL27444751 | 0.83 | MME (0.55) | TACR1MMEACECPA1ACE2 | |
| SCHEMBL27446259 | 0.83 | OPRM1 (0.45) | TACR1MMEACECTSBPOLB | |
| SCHEMBL8017170 | 0.83 | MME (0.61) | TACR1MMEACECTSLCTSB | |
| SCHEMBL8017176 | 0.82 | MME (0.59) | MMEACECTSBCPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |