Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021483 | 0.89 | HTR6 (0.33) | NFKB1KDM4ELMNATP53CHRM2 | |
| SCHEMBL1028711 | 0.82 | HTR6 (0.47) | BCHEACHENFKB1KDM4ELMNA | |
| SCHEMBL5970701 | 0.82 | HTR6 (0.35) | HTR2AHTR6SIGMAR1 | |
| SCHEMBL29546963 | 0.77 | HTR6 (0.46) | BCHEACHENFKB1KDM4ELMNA | |
| SCHEMBL2641527 | 0.77 | HTR6 (0.46) | BCHEACHENFKB1KDM4ELMNA | |
| SCHEMBL6674209 | 0.76 | HTR6 (0.45) | NFKB1KDM4ELMNATP53CHRM2 | |
| SCHEMBL6055948 | 0.76 | HTR6 (0.45) | NFKB1KDM4ELMNATP53CHRM2 | |
| SCHEMBL31185871 | 0.76 | HTR6 (0.45) | NFKB1KDM4ELMNATP53CHRM2 | |
| SCHEMBL30679045 | 0.76 | HTR6 (0.45) | NFKB1KDM4ELMNATP53CHRM2 | |
| SCHEMBL10359804 | 0.76 | HTR6 (0.45) | NFKB1KDM4ELMNATP53CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986567-A1 | PURE ENANTIOMER METALLOCENE COMPLEXES AND THE PRODUCTION AND USE OF THE SAME | Ringwald, Markus (DE) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998052956-A1 | PURE ENANTIOMER METALLOCENE COMPLEXES AND THE PRODUCTION AND USE OF THE SAME | RINGWALD MARKUS (DE) | 1998-11-26 | — | — | WO | disclosed |