Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39946 | 0.78 | ESR1 (0.44) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| SCHEMBL9818045 | 0.78 | ESR1 (0.44) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| SCHEMBL11032897 | 0.76 | CHKA (0.46) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| SCHEMBL16371884 | 0.76 | ESR1 (0.43) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL28398668 | 0.76 | ESR1 (0.43) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| Water SCHEMBL10786878 | 0.76 | ESR1 (0.43) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| SCHEMBL83762 | 0.76 | CHKA (0.46) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4050783 | 0.74 | CHKA (0.44) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| SCHEMBL8516543 | 0.74 | ESR1 (0.42) | S1PR1ESR1CYP1A2KMT2AMEN1 | |
| SCHEMBL9279908 | 0.74 | ESR1 (0.42) | S1PR1ESR1CYP1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115378-A | TEXTILES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-19 | — | — | US | claimed |
| US-10570150-B2 | 6,7-trans cephalosporin-based probes for detecting bacteria expressing a metallo-beta-lactamase | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-02-25 | — | — | US | disclosed |
| CN-107922430-A | 2 substituted benzimidazole, 4 Carbox amide and preparation method and application | 中国科学院上海药物研究所 | 2018-04-17 | — | — | CN | disclosed |
| CN-106317069-A | 2-substituted-benzimidazole-4-formamide compound, preparation method, and application thereof | 中国科学院上海药物研究所 | 2017-01-11 | — | — | CN | disclosed |
| WO-2016206651-A1 | 2-SUBSTITUTED BENZIMIDAZOLE-4-CARBOXAMIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 中国科学院上海药物研究所 | 2016-12-29 | — | — | WO | disclosed |
| EP-3094623-A1 | 6,7-TRANS CEPHALOSPORIN-BASED PROBES FOR DETECTING BACTERIA EXPRESSING A METALLO- -LACTAMASE | The Board of Trustees of The Leland Stanford Junior University (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160333027-A1 | 6,7-TRANS CEPHALOSPORIN-BASED PROBES FOR DETECTING BACTERIA EXPRESSING A METALLO-BETA-LACTAMASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2016-11-17 | — | — | US | disclosed |
| WO-2015109056-A1 | 6,7-TRANS CEPHALOSPORIN-BASED PROBES FOR DETECTING BACTERIA EXPRESSING A METALLO-β-LACTAMASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-07-23 | — | — | WO | disclosed |
| US-6117950-A | MODIFIED WITH EPOXY RESIN | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 2000-09-12 | — | — | US | disclosed |
| US-6037422-A | HAVING IMPROVED MECHANICAL PROPERTIES SUCH AS IMPACT RESISTANCE AND BENDING STRENGTH, WHILE MAINTAINING HEAT RESISTANCE AND FIRE RETARDANCY | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 2000-03-14 | — | — | US | disclosed |
| EP-0424939-B1 | Polyarylene sulfide resin compositions | IDEMITSU PETROCHEMICAL CO (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5422211-A | Imaging members with trisazo photogenerating materials | XEROX CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0424939-A2 | Polyarylene sulfide resin compositions | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 1991-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160333027-A1 | 6,7-TRANS CEPHALOSPORIN-BASED PROBES FOR DETECTING BACTERIA EXPRESSING A METALLO-BETA-LACTAMASE | CMBL, MGAM, GUSB | S1PR1 4767/4885ESR1 2630/4885CYP1A2 1720/4885 |
| US-10570150-B2 | 6,7-trans cephalosporin-based probes for detecting bacteria expressing a metallo-beta-lactamase | CMBL, MGAM, GUSB | S1PR1 4760/4885ESR1 2652/4885CYP1A2 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.