Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029008 | 0.79 | CCR6 (0.56) | CCR6PAX8MAPTHDAC1HDAC2 | |
| SCHEMBL8030776 | 0.78 | CCR6 (0.54) | TSHRCCR6PAX8ALDH1A1MAPT | |
| SCHEMBL9110508 | 0.77 | CCR6 (0.61) | CCR6PAX8ALDH1A1MC4RMC5R | |
| SCHEMBL15582141 | 0.77 | CCR6 (0.61) | CCR6PAX8ALDH1A1MC4RMC5R | |
| SCHEMBL19018818 | 0.77 | CCR6 (0.61) | CCR6PAX8ALDH1A1MC4RMC5R | |
| SCHEMBL13485433 | 0.77 | CCR6 (0.44) | TSHRFAAHMGLLCCR6PAX8 | |
| SCHEMBL8032609 | 0.77 | MEN1 (0.54) | CCR6PAX8ALDH1A1CYP3A4HTT | |
| SCHEMBL6264786 | 0.77 | CCR6 (0.57) | CCR6PAX8ALDH1A1HDAC1HDAC2 | |
| SCHEMBL14823650 | 0.77 | CCR6 (0.56) | CCR6PAX8ALDH1A1HDAC1HDAC2 | |
| SCHEMBL16586897 | 0.76 | CCR6 (0.63) | CCR6PAX8ALDH1A1NPSR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |