Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029008 | 0.81 | CCR6 (0.56) | KMT2ACCR6PAX8PTGDR2LMNA | |
| SCHEMBL15582141 | 0.79 | CCR6 (0.61) | MEN1KMT2ACCR6PAX8ALDH1A1 | |
| SCHEMBL19018818 | 0.79 | CCR6 (0.61) | MEN1KMT2ACCR6PAX8ALDH1A1 | |
| SCHEMBL9110508 | 0.79 | CCR6 (0.61) | MEN1KMT2ACCR6PAX8ALDH1A1 | |
| SCHEMBL6264786 | 0.79 | CCR6 (0.57) | MEN1KMT2ACCR6PAX8LMNA | |
| SCHEMBL14823650 | 0.79 | CCR6 (0.56) | MEN1KMT2ACCR6PAX8LMNA | |
| SCHEMBL16586897 | 0.78 | CCR6 (0.63) | MEN1KMT2ACCR6PAX8LMNA | |
| SCHEMBL554069 | 0.77 | CCR6 (0.64) | KMT2ACCR6PAX8MMP12LMNA | |
| SCHEMBL8030822 | 0.77 | TSHR (0.52) | CCR6PAX8CYP3A4GAAALDH1A1 | |
| SCHEMBL8030776 | 0.77 | CCR6 (0.54) | MEN1KMT2ACCR6PAX8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |