SCHEMBL8030870

SCHEMBL8030870

[NH]C(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
MMP2 P08253 1/20 0.38
THRB P10828 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LAP3 P28838 2/20 0.33
ANPEP P15144 1/20 0.33
ERAP2 Q6P179 1/20 0.33
TYMS P04818 1/20 0.33
CA2 P00918 1/20 0.33
FDPS P14324 2/20 0.32
SLC34A1 Q06495 1/20 0.31
PGK1 P00558 3/20 0.30
PGK2 P07205 3/20 0.30
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3084158 0.72
SCHEMBL919194 0.64
SCHEMBL4105786 0.64 KDM4E (0.43) KDM4EMMP2THRBMAPK1HSD17B10
SCHEMBL1409859 0.64 KDM4E (0.43) KDM4EMMP2THRBMAPK1HSD17B10
Phosphoric Acid SCHEMBL11132493 0.61
SCHEMBL318686 0.61
SCHEMBL11436271 0.61
Phosphoric Acid SCHEMBL27534908 0.61 CA2 (0.46) KDM4EMMP2THRBMAPK1HSD17B10
SCHEMBL9683090 0.61
SCHEMBL4124787 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0831065-B1 A method and a composition for controlling scale in an aqueous system using a synergistic composition CALGON CORP (US) 2000-07-19 EP disclosed
EP-0564232-B1 N,N-bis(phosphonomethyl)-2-amino-1-propanol derivatives for high pH scale control CALGON CORP (US) 2000-06-07 EP disclosed
EP-0767145-B1 Use of a synergistic composition for scale control CALGON CORP (US) 2000-03-15 EP disclosed
EP-0711733-B1 Polyether polyamino methylene phosphonates for high pH scale control CALGON CORP (US) 1999-08-25 EP disclosed
EP-0593250-B1 Synergistic antimicrobial combination of polyether phosphonates and non-oxidizing biocides CALGON CORP (US) 1998-12-02 EP disclosed
US-5772913-A POLYETHER POLYAMINO METHYLENE PHOSPHONATE, TERPOLYMER OF ACRYLIC ACID, SULFOPHENOXYMETHALLYL ETHER AND MALEIC ACID, HYDROXYPHOSPHONOACETIC ACID, PHOSPHONOCARBOXYLIC ACID COPOLYMER CALGON CORPORATION (US) 1998-06-30 US disclosed
EP-0831065-A1 A method for controlling scale in an aqueous system using a synergistic composition Calgon Corporation (US) 1998-03-25 EP disclosed
US-5709814-A POLYETHER POLYAMINOMETHYLENE PHOSPHONATE CALGON CORPORATION (US) 1998-01-20 US disclosed
US-5707529-A SYNERGISTIC MIXTURE CONTAINING POLYETHER TETRAKIS/AMINOMETHYLENEPHOSPHONATE/ CALGON CORPORATION (US) 1998-01-13 US disclosed
US-5702634-A MIXTURE CONTAINING TERPOLYMER OF ACRYLIC ACID, SULFOPHENOMETHALLYL ETHER AND MALEIC ACID CALGON CORPORATION (US) 1997-12-30 US disclosed
US-5358642-A Preventing deposits or corrosion in water supply systems having high concentrations of dissolved calcium carbonate CALGON CORPORATION (US) 1994-10-25 US disclosed
US-5338477-A Polyether polyamino methylene phosphonates for high pH scale control CALGON CORPORATION (US) 1994-08-16 US disclosed
US-5322636-A Polyether polyamino methylene phosphonate n-oxides for high pH scale control CALGON CORPORATION (US) 1994-06-21 US disclosed
EP-0593250-A1 Synergistic antimicrobial combination of polyether phosphonates and non-oxidizing biocides Calgon Corporation (US) 1994-04-20 EP disclosed
US-5300231-A Controlling silica/silicate deposition using phosphonate combinations CALGON CORPORATION (US) 1994-04-05 US disclosed
EP-0577422-A1 Zinc, iron and manganese stabilization using polyeter polyamino methylene phosphonates Calgon Corporation (US) 1994-01-05 EP disclosed
US-5262061-A INHIBITING PRECIPITATION OF DISSOLVED ZINC, IRON AND MANGANESE, AND THEIR REACTION PRODUCTS, IN WATER SUPPLY SYSTEMS CALGON CORPORATION (US) 1993-11-16 US disclosed
US-5259974-A High dissolved solids, and high levels of calcium carbonate CALGON CORPORATION (US) 1993-11-09 US disclosed
EP-0564232-A1 N,N-bis(phosphonomethyl)-2-amino-1-propanol derivatives for high pH scale control Calgon Corporation (US) 1993-10-06 EP disclosed
EP-0516382-A1 Polyether polyamino methylene phosphonates for high pH scale control Calgon Corporation (US) 1992-12-02 EP disclosed