⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540162 | 1.00 | — | — | |
| SCHEMBL8030874 | 1.00 | — | — | |
| SCHEMBL9538511 | 0.79 | S1PR2 (0.44) | — | |
| SCHEMBL9538508 | 0.79 | S1PR2 (0.44) | — | |
| SCHEMBL23010664 | 0.77 | — | — | |
| SCHEMBL19987638 | 0.77 | — | — | |
| SCHEMBL1763282 | 0.74 | — | — | |
| SCHEMBL13535333 | 0.74 | — | — | |
| SCHEMBL9536101 | 0.72 | L3MBTL1 (0.33) | — | |
| SCHEMBL9536106 | 0.72 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981358-A1 | DOLASTATIN-15 DERIVATIVES IN COMBINATION WITH TAXANES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-01 | — | — | EP | claimed |
| WO-1998040092-A1 | DOLASTATIN-15 DERIVATIVES IN COMBINATION WITH TAXANES | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | claimed |