Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536106 | 1.00 | L3MBTL1 (0.33) | L3MBTL1SMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL11653000 | 0.78 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL11126675 | 0.78 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL8030871 | 0.72 | — | — | |
| SCHEMBL8030874 | 0.72 | — | — | |
| SCHEMBL12128028 | 0.69 | L3MBTL1 (0.33) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL12305635 | 0.69 | L3MBTL1 (0.33) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL9536112 | 0.69 | L3MBTL1 (0.33) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL28795006 | 0.69 | ADH1B (0.32) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL2695913 | 0.69 | L3MBTL1 (0.38) | L3MBTL1SMN1; SMN2ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182262-B1 | NONA AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| EP-0097031-B1 | NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4690916-A | ANTIFERTILITY AGENTS; HALO-SUBSTITUTED GUANADINO AMINO ACYL RESIDUE COMPONENT | SYNTEX (U.S.A.) INC. (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0182262-A2 | Nona and decapeptide analogs of LHRH useful as LHRH antagonists | SYNTEX (U.S.A.) INC. (US) | 1986-05-28 | — | — | EP | disclosed |
| US-4581169-A | Nona-peptide and deca-peptide analogs of LHRH, useful as LHRH antagonists | SYNTEX (U.S.A.) INC. (US) | 1986-04-08 | — | — | US | disclosed |
| US-4481190-A | LUTEINIZING HORMONE RELEASING HORMONE | SYNTEX (U.S.A.) INC. (US) | 1984-11-06 | — | — | US | disclosed |
| EP-0097031-A2 | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, their preparation and compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1983-12-28 | — | — | EP | disclosed |