Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | LDHB | P07195 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041784 | 0.88 | DPP4 (0.36) | DPP4LDHALDHBKMT2AKDM4E | |
| SCHEMBL5589377 | 0.81 | DPP4 (0.45) | DPP4LDHALDHBKDM4EIMPDH2 | |
| SCHEMBL7322400 | 0.73 | KDM4E (0.41) | LDHALDHBKMT2AKDM4EALDH1A1 | |
| SCHEMBL13154636 | 0.73 | KDM4E (0.41) | LDHALDHBKMT2AKDM4EALDH1A1 | |
| SCHEMBL28743710 | 0.73 | ALDH1A1 (0.41) | DPP4LDHALDHBKMT2AKDM4E | |
| SCHEMBL31643709 | 0.72 | DPP4 (0.40) | DPP4LDHALDHBKMT2AKDM4E | |
| SCHEMBL14718570 | 0.72 | DPP4 (0.45) | DPP4LDHALDHBKMT2AKDM4E | |
| SCHEMBL5692889 | 0.71 | KDM4E (0.42) | LDHALDHBKMT2AKDM4EALDH1A1 | |
| SCHEMBL27421518 | 0.71 | ALDH1A1 (0.40) | DPP4LDHALDHBKMT2AKDM4E | |
| SCHEMBL12257172 | 0.71 | KDM4E (0.42) | LDHALDHBKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686144-B1 | NEW COMPOUNDS | UNIV MARYLAND (US) | 2000-04-19 | — | — | EP | disclosed |
| US-5688945-A | Compounds | ASTRA AKTIEBOLAG (SE) | 1997-11-18 | — | — | US | disclosed |
| US-5661183-A | 3-hydroxy anthanilic acid derivatives | THE UNIVERSITY OF MARYLAND (US) | 1997-08-26 | — | — | US | disclosed |
| CN-1121344-A | New compounds | ASTRA AB (SE) | 1996-04-24 | — | — | CN | disclosed |
| EP-0686144-A1 | NEW COMPOUNDS | Astra Aktiebolag (SE) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994019315-A1 | NEW COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1994-09-01 | — | — | WO | disclosed |