Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289853 | 0.84 | ALDH1A1 (0.49) | RAF1DAOALDH1A1RAB9ANPC1 | |
| SCHEMBL1694410 | 0.80 | DAO (0.52) | RAF1DAORAB9ANPC1KMT2A | |
| SCHEMBL28196751 | 0.79 | RAF1 (0.46) | RAF1DAOALDH1A1RAB9ANPC1 | |
| SCHEMBL29183917 | 0.79 | CYP1A2 (0.51) | RAF1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11471040 | 0.79 | HSD17B10 (0.48) | TSHRRAF1DAOSMN1; SMN2ADORA3 | |
| SCHEMBL7757560 | 0.77 | DAO (0.44) | RAF1DAOPOLBKMT2ATP53 | |
| SCHEMBL13787409 | 0.76 | RAF1 (0.43) | RAF1DAOALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28197504 | 0.74 | POLB (0.49) | TSHRALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7279134 | 0.73 | CHRM5 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL6821316 | 0.73 | HDAC1 (0.35) | RAF1DAOALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073719-A1 | QUINOXALINYL DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-11 | — | — | WO | disclosed |