SCHEMBL7757560

SCHEMBL7757560

Cc1csc(NC(N)=O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.44
RAF1 P04049 1/20 0.43
KIF11 P52732 1/20 0.40
SYK P43405 1/20 0.35
GAA P10253 3/20 0.34
TP53 P04637 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HDAC1 Q13547 3/20 0.33
HDAC2 Q92769 3/20 0.33
HDAC3 O15379 2/20 0.33
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
NR3C2 P08235 1/20 0.33
LMNA P02545 2/20 0.33
CDK8 P49336 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1694410 0.83 DAO (0.52) DAORAF1GAATP53MEN1
SCHEMBL11471040 0.82 HSD17B10 (0.48) DAORAF1GAAMEN1KMT2A
SCHEMBL11486489 0.80 CYP1A2 (0.43) DAORAF1SYKGAATP53
SCHEMBL13787409 0.78 RAF1 (0.43) DAORAF1GAATP53MEN1
SCHEMBL8031103 0.77 TSHR (0.44) DAORAF1GAATP53MEN1
SCHEMBL7289853 0.76 ALDH1A1 (0.49) DAORAF1GAAKMT2AMAPT
SCHEMBL14981726 0.76 RAF1 (0.36) DAORAF1SYK
SCHEMBL29183917 0.74 CYP1A2 (0.51) RAF1MEN1KMT2AHDAC1HDAC2
SCHEMBL28196767 0.74 GAA (0.54) DAORAF1GAATP53MEN1
SCHEMBL28196751 0.74 RAF1 (0.46) DAORAF1GAATP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed
US-5441984-A Antidiabetic agent ELI LILLY AND COMPANY (US) 1995-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 DAO 4147/4885RAF1 3815/4885KIF11 2646/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 DAO 4147/4885RAF1 3815/4885KIF11 2646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.